OTUD5 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all OTUD5 Proteins
- OTUD5 (OTU Domain Containing 5 (OTUD5))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This OTUD5 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human OTUD5 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product OTUD5 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- OTUD5 (OTU Domain Containing 5 (OTUD5))
- Alternative Name
- Otud5 (OTUD5 Products)
- Synonyms
- DUBA Protein, AA407879 Protein, AI553596 Protein, BB114028 Protein, DXImx46e Protein, Sfc7 Protein, otud5 Protein, si:bz30i22.1 Protein, si:rp71-30i22.1 Protein, zgc:154072 Protein, wu:fi28a06 Protein, zgc:100839 Protein, OTU deubiquitinase 5 Protein, OTU domain containing 5 Protein, OTU deubiquitinase 5a Protein, OTU deubiquitinase 5 S homeolog Protein, OTU deubiquitinase 5 L homeolog Protein, OTU deubiquitinase 5b Protein, OTUD5 Protein, Otud5 Protein, otud5a Protein, otud5.S Protein, otud5.L Protein, otud5b Protein
- Background
- This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described.
- Molecular Weight
- 60.4 kDa
- NCBI Accession
- NP_060072
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