PACRG Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Target See all PACRG Proteins
- PACRG (PARK2 Co-Regulated (PACRG))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PACRG protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human PACRG (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PACRG Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- PACRG (PARK2 Co-Regulated (PACRG))
- Alternative Name
- Pacrg (PACRG Products)
- Synonyms
- PACRG Protein, GLUP Protein, HAK005771 Protein, PARK2CRG Protein, RP3-495O10.2 Protein, zgc:101786 Protein, RGD1561027 Protein, 1700008H23Rik Protein, parkin coregulated Protein, PARK2 co-regulated Protein, PARK2 coregulated Protein, PACRG Protein, pacrg Protein, Pacrg Protein
- Background
- This gene encodes a protein that is conserved across metazoans. In vertebrates, this gene is linked in a head-to-head arrangement with the adjacent parkin gene, which is associated with autosomal recessive juvenile Parkinson's disease. These genes are co-regulated in various tissues and they share a bi-directional promoter. Both genes are associated with susceptibility to leprosy. The parkin co-regulated gene protein forms a large molecular complex with chaperones, including heat shock proteins 70 and 90, and chaperonin components. This protein is also a component of Lewy bodies in Parkinson's disease patients, and it suppresses unfolded Pael receptor-induced neuronal cell death. Multiple transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
- 29.1 kDa
- NCBI Accession
- NP_001073847
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