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PAK7 Protein (Transcript Variant 2)

PAK7 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD, Func, PI Active
Catalog No. ABIN2728183
  • Target See all PAK7 Proteins
    PAK7 (P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    Transcript Variant 2
    Origin
    • 3
    • 1
    • 1
    Human
    Source
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Application
    Antibody Production (AbP), Standard (STD), Functional Studies (Func), Protein Interaction (PI)
    Specificity
    Optimal preservation of protein structure, post-translational modifications and functions.
    Characteristics
    • Recombinant human PAK7 / PAK5 (transcript variant 2) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    • Tested for bioactivity.
    Purity
    > 90 % as determined by SDS-PAGE and Coomassie blue staining
    Endotoxin Level
    <0.1 ng/μg of protein (<1EU/μg).
    Biological Activity Comment
    Specific activity was determined as 4,199 pmoles/min/μg, according to the Zlyte assay protocol
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    Discover our top product PAK7 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    25 mM Tris-HCl pH 8.0, 150 mM NaCl, 10 % glycerol, 5 mM DTT.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    PAK7 (P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7))
    Alternative Name
    Pak7,pak5 (PAK7 Products)
    Synonyms
    PAK5 Protein, pak5 Protein, 2900083L08Rik Protein, 6430627N20 Protein, Pak5 Protein, PAK-5 Protein, PAK-7 Protein, p21 (RAC1) activated kinase 5 Protein, p21 (RAC1) activated kinase 5 L homeolog Protein, p21 protein (Cdc42/Rac)-activated kinase 7 Protein, p21 (RAC1) activated kinase 7 Protein, PAK5 Protein, pak5.L Protein, Pak7 Protein
    Background
    The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described.
    Molecular Weight
    33.9 kda
    NCBI Accession
    NP_817127
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