PCDHGA2 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Target See all PCDHGA2 Proteins
- PCDHGA2 (Protocadherin gamma Subfamily A, 2 (PCDHGA2))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PCDHGA2 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human PCDHGA2 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PCDHGA2 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- PCDHGA2 (Protocadherin gamma Subfamily A, 2 (PCDHGA2))
- Alternative Name
- Pcdhga2 (PCDHGA2 Products)
- Synonyms
- PCDH-GAMMA-A2 Protein, mKIAA0588 Protein, PCDHGA1 Protein, PCDHGA5 Protein, PCDHGB3 Protein, PCDHGB7 Protein, protocadherin gamma subfamily A, 2 Protein, protocadherin gamma subfamily A, 2-like Protein, protocadherin gamma-A2-like Protein, protocadherin gamma-C4 Protein, PCDHGA2 Protein, Pcdhga2 Protein, PCDHGA2L Protein, LOC100523539 Protein, LOC100353508 Protein, pcdhga2 Protein
- Background
- This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
- Molecular Weight
- 87 kDa
- NCBI Accession
- NP_114398
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