PDE5A Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Target See all PDE5A Proteins
- PDE5A (phosphodiesterase 5A, cGMP-Specific (PDE5A))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PDE5A protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human PDE5A (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PDE5A Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- PDE5A (phosphodiesterase 5A, cGMP-Specific (PDE5A))
- Alternative Name
- Pde5a (PDE5A Products)
- Synonyms
- CGB-PDE Protein, CN5A Protein, PDE5 Protein, PDE5A2 Protein, Cgbpde Protein, Cn5n Protein, Pde5 Protein, Pde5a1 Protein, PDE5A Protein, pde5a Protein, cgb-pde Protein, cn5a Protein, pde5 Protein, pde5a1 Protein, phosphodiesterase 5A Protein, phosphodiesterase 5A, cGMP-specific Protein, phosphodiesterase 5A S homeolog Protein, phosphodiesterase 5A, cGMP-specific, b Protein, PDE5A Protein, Pde5a Protein, pde5a.S Protein, pde5ab Protein, pde5a Protein
- Background
- This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5&apos-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.
- Molecular Weight
- 94.6 kDa
- NCBI Accession
- NP_236914
- Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling
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