PEX5 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Target See all PEX5 Proteins
- PEX5 (Peroxisomal Biogenesis Factor 5 (PEX5))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PEX5 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Peroxin 5 / PEX5 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PEX5 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- PEX5 (Peroxisomal Biogenesis Factor 5 (PEX5))
- Alternative Name
- Peroxin 5,pex5 (PEX5 Products)
- Synonyms
- AW212715 Protein, ESTM1 Protein, PTS1R Protein, Pxr1 Protein, X83306 Protein, PTS1-BP Protein, PBD2A Protein, PBD2B Protein, PXR1 Protein, Peroxin-5 Protein, peroxisomal biogenesis factor 5 Protein, pex5 Protein, Pex5 Protein, PEX5 Protein
- Background
- The product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified.
- Molecular Weight
- 69.7 kDa
- NCBI Accession
- NP_000310
- Pathways
- Monocarboxylic Acid Catabolic Process
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