BPIFA1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all BPIFA1 Proteins
- BPIFA1 (BPI Fold Containing Family A, Member 1 (BPIFA1))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This BPIFA1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human PLUNC (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product BPIFA1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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Anti-BPIFA1/SPLUNC1: a new autoantibody prevalent in patients with endstage cystic fibrosis." in: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, Vol. 13, Issue 3, pp. 281-8, (2014) (PubMed).
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Anti-BPIFA1/SPLUNC1: a new autoantibody prevalent in patients with endstage cystic fibrosis." in: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, Vol. 13, Issue 3, pp. 281-8, (2014) (PubMed).
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- Target
- BPIFA1 (BPI Fold Containing Family A, Member 1 (BPIFA1))
- Alternative Name
- Plunc (BPIFA1 Products)
- Synonyms
- LUNX Protein, NASG Protein, PLUNC Protein, SPLUNC1 Protein, SPURT Protein, bA49G10.5 Protein, Plunc Protein, BPI fold containing family A member 1 Protein, BPI fold containing family A, member 1 Protein, BPIFA1 Protein, Bpifa1 Protein
- Background
- This gene is the human homolog of murine plunc, and like the mouse gene, is specifically expressed in the upper airways and nasopharyngeal regions. The encoded antimicrobial protein displays antibacterial activity against Gram-negative bacteria. It is thought to be involved in inflammatory responses to irritants in the upper airways and may also serve as a potential molecular marker for detection of micrometastasis in non-small-cell lung cancer. Multiple transcript variants resulting from alternative splicing in the 3&apos UTR have been detected, but the full-length nature of only three are known.
- Molecular Weight
- 24.6 kDa
- NCBI Accession
- NP_057667
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