PRDM2 Protein (Transcript Variant 4) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2729561

Product Details

Target: PRDM2 (PR Domain Containing 2, with ZNF Domain (PRDM2))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 4

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This PRDM2 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human PRDM2 (transcript variant 4) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: PRDM2 (PR Domain Containing 2, with ZNF Domain (PRDM2))

Alternative Name: Prdm2 (PRDM2 Products)

Synonyms: MGC114763 Protein, prdm2 Protein, riz Protein, kmt8 Protein, riz1 Protein, riz2 Protein, mtb-zf Protein, humhoxy1 Protein, PRDM2 Protein, HUMHOXY1 Protein, KMT8 Protein, MTB-ZF Protein, RIZ Protein, RIZ1 Protein, RIZ2 Protein, 4833427P12Rik Protein, E330024L24Rik Protein, Gm1033 Protein, Gm19732 Protein, Riz Protein, Riz1 Protein, Znfpr1c1 Protein, PR domain containing 2, with ZNF domain S homeolog Protein, PR domain containing 2, with ZNF domain b Protein, PR domain containing 2, with ZNF domain Protein, PR domain zinc finger protein 2 Protein, PR/SET domain 2 Protein, prdm2.S Protein, prdm2b Protein, prdm2 Protein, LOC100350859 Protein, PRDM2 Protein, Prdm2 Protein

Background: This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 25.3 kDa

NCBI Accession: NP_001129082