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PRDM2 Products

(PR Domain Containing 2, with ZNF Domain (PRDM2))

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This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008].

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Featured PRDM2 Categories

PRDM2 Antibodies

High quality antibodies with extensive validation data.

PRDM2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PRDM2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, ChIP
Validations
  • (2)
  • (4)
Cat. No. ABIN387783
Quantity 400 μL
Datasheet Datasheet
Reactivity Rat
Application IHC
Validations
  • (5)
Cat. No. ABIN7264615
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, ChIP
Validations
  • (6)
Cat. No. ABIN3032300
Quantity 0.4 mL
Datasheet Datasheet

Recommended PRDM2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6951135
Quantity 96 tests
Datasheet Datasheet

Recommended PRDM2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124542
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316143
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7317620
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our PRDM2 products

Cheng, Gao, Lou: "DNA methylation of the RIZ1 tumor suppressor gene plays an important role in the tumorigenesis of cervical cancer." in: European journal of medical research, Vol. 15, Issue 1, pp. 20-4, (2010) (PubMed).

Harsløf, Husted, Carstens, Stenkjaer, Langdahl: "Genotypes and haplotypes of the estrogen receptor genes, but not the retinoblastoma-interacting zinc finger protein 1 gene, are associated with osteoporosis." in: Calcified tissue international, Vol. 87, Issue 1, pp. 25-35, (2010) (PubMed).

Lakshmikuttyamma, Takahashi, Pastural, Torlakovic, Amin, Garcia-Manero, Voralia, Czader, DeCoteau, Geyer: "RIZ1 is potential CML tumor suppressor that is down-regulated during disease progression." in: Journal of hematology & oncology, Vol. 2, pp. 28, (2009) (PubMed).

de Vogel, Wouters, Gottschalk, van Schooten, de Goeij, de Bruïne, Goldbohm, van den Brandt, Weijenberg, van Engeland: "Genetic variants of methyl metabolizing enzymes and epigenetic regulators: associations with promoter CpG island hypermethylation in colorectal cancer." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 18, Issue 11, pp. 3086-96, (2009) (PubMed).

Carling, Kim, Yang, Gu, Zhang, Huang: "A histone methyltransferase is required for maximal response to female sex hormones." in: Molecular and cellular biology, Vol. 24, Issue 16, pp. 7032-42, (2004) (PubMed).

Synonyms and alternative names related to PRDM2

PR domain containing 2, with ZNF domain S homeolog (prdm2.S), PR domain containing 2, with ZNF domain b (prdm2b), PR domain containing 2, with ZNF domain (prdm2), PR domain zinc finger protein 2 (LOC100350859), PR/SET domain 2 (PRDM2), PR domain containing 2, with ZNF domain (Prdm2), PR/SET domain 2 (Prdm2), 4833427P12Rik, E330024L24Rik, Gm1033, Gm19732, humhoxy1, HUMHOXY1, kmt8, KMT8, MGC114763, mtb-zf, MTB-ZF, prdm2, PRDM2, riz, RIZ, Riz, riz1, RIZ1, Riz1, riz2, RIZ2, Znfpr1c1

Protein level used designations for PRDM2

  • PR domain containing 2, with ZNF domain
  • retinoblastoma protein-binding zinc finger protein-like
  • PR domain zinc finger protein 2-like
  • GATA-3 binding protein G3B
  • GATA-3-binding protein G3B
  • MTE-binding protein
  • PR domain zinc finger protein 2
  • PR domain-containing protein 2
  • lysine N-methyltransferase 8
  • retinoblastoma protein-binding zinc finger protein
  • retinoblastoma protein-interacting zinc finger protein
  • zinc finger protein RIZ
  • zinc-finger DNA-binding protein
  • retinoblastoma interacting zinc finger protein
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