Prostaglandin E Synthase Protein (PTGES) (Myc-DYKDDDDK Tag)
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- Target See all Prostaglandin E Synthase (PTGES) Proteins
- Prostaglandin E Synthase (PTGES)
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Prostaglandin E Synthase protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human PTGES protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PTGES Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- Prostaglandin E Synthase (PTGES)
- Alternative Name
- Ptges (PTGES Products)
- Synonyms
- ptges Protein, MGC80290 Protein, PTGES Protein, MGST-IV Protein, MGST1-L1 Protein, MGST1L1 Protein, MPGES Protein, PGES Protein, PIG12 Protein, PP102 Protein, PP1294 Protein, TP53I12 Protein, mPGES-1 Protein, 2410099E23Rik Protein, D2Ertd369e Protein, Pges Protein, mPGES Protein, MPGES-1 Protein, prostaglandin E synthase Protein, prostaglandin E synthase S homeolog Protein, PTGES Protein, ptges.S Protein, Ptges Protein
- Background
- The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses.
- Molecular Weight
- 16.9 kDa
- NCBI Accession
- NP_004869
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