PTPRE Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all PTPRE Proteins
- PTPRE (Protein tyrosine Phosphatase, Receptor Type, E (PTPRE))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PTPRE protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human PTPRE (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PTPRE Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- PTPRE (Protein tyrosine Phosphatase, Receptor Type, E (PTPRE))
- Alternative Name
- Ptpre (PTPRE Products)
- Synonyms
- ptpra Protein, HPTPE Protein, PTPE Protein, R-PTP-EPSILON Protein, PTPe Protein, PTPepsilon Protein, RPTPepsilon Protein, protein tyrosine phosphatase, receptor type E L homeolog Protein, protein tyrosine phosphatase, receptor type E Protein, protein tyrosine phosphatase, receptor type, E Protein, ptpre.L Protein, PTPRE Protein, Ptpre Protein
- Background
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Several alternatively spliced transcript variants of this gene have been reported, at least two of which encode a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokine-induced SATA signaling, as well as the activation of voltage-gated K+ channels.
- Molecular Weight
- 80.5 kDa
- NCBI Accession
- NP_006495
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