RACGAP1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Target See all RACGAP1 Proteins
- RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This RACGAP1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human RACGAP1 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product RACGAP1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))
- Alternative Name
- Racgap1 (RACGAP1 Products)
- Synonyms
- CYK4 Protein, HsCYK-4 Protein, ID-GAP Protein, MgcRacGAP Protein, cyk-4 Protein, id-gap Protein, mgcracgap Protein, RACGAP1 Protein, MGC121578 Protein, Gap Protein, RasGAP Protein, Rasa Protein, GAPX Protein, AI227039 Protein, AI327394 Protein, Band25 Protein, GTPase Protein, gtl11 Protein, mKIAA1478 Protein, wu:fb92c08 Protein, zgc:77839 Protein, Rac GTPase activating protein 1 Protein, rac GTPase-activating protein 1 Protein, Rac GTPase activating protein 1 L homeolog Protein, RAS p21 protein activator 1 Protein, Rac GTPase-activating protein 1 Protein, si:ch1073-416j23.1 Protein, RACGAP1 Protein, racgap1 Protein, racgap1.L Protein, racgap1.2.L Protein, racgap1.2 Protein, Rasa1 Protein, Racgap1 Protein, si:ch1073-416j23.1 Protein
- Background
- This gene encodes a GTPase-activating protein (GAP) that is a compoment of the centralspindlin complex. This protein binds activated forms of Rho GTPases and stimulates GTP hydrolysis, which results in negative regulation of Rho-mediated signals. This protein plays a regulatory role in cytokinesis, cell growth, and differentiation. Alternatively spliced transcript variants have been found for this gene. There is a pseudogene for this gene on chromosome 12.
- Molecular Weight
- 70.8 kDa
- NCBI Accession
- NP_001119575
- Pathways
- Regulation of Actin Filament Polymerization, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling of Hepatocyte Growth Factor Receptor
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