RNF34 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Target See all RNF34 Proteins
- RNF34 (Ring Finger Protein 34 (RNF34))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This RNF34 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human RFI / RNF34 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product RNF34 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- RNF34 (Ring Finger Protein 34 (RNF34))
- Alternative Name
- Rfi,rnf34 (RNF34 Products)
- Synonyms
- CARP-1 Protein, CARP1 Protein, RFI Protein, RIF Protein, RIFF Protein, hRFI Protein, rnf34 Protein, AW061037 Protein, AW536122 Protein, BC004042 Protein, C88279 Protein, Momo Protein, fi35g06 Protein, wu:fi35g06 Protein, zgc:114043 Protein, zgc:171755 Protein, ring finger protein 34 Protein, E3 ubiquitin-protein ligase RNF34 Protein, ring finger protein 34a Protein, ring finger protein 34b Protein, Residual feed intake Protein, RNF34 Protein, rnf34 Protein, Rnf34 Protein, rnf34a Protein, rnf34b Protein, RFI Protein
- Background
- The protein encoded by this gene contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. This protein also targets p53 and phospho-p53 for degradation. Alternatively splicing results in multiple transcript variants encoding distinct isoforms.
- Molecular Weight
- 41.5 kDa
- NCBI Accession
- NP_079402
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