GRK1 Protein (Myc-DYKDDDDK Tag)
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- Target See all GRK1 Proteins
- GRK1 (G Protein-Coupled Receptor Kinase 1 (GRK1))
- Protein Type
- Recombinant
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This GRK1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Rhodopsin kinase protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product GRK1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- GRK1 (G Protein-Coupled Receptor Kinase 1 (GRK1))
- Alternative Name
- Rhodopsin Kinase (GRK1 Products)
- Synonyms
- GPRK1 Protein, RHOK Protein, RK Protein, Gprk1 Protein, Rhok Protein, Rk Protein, CG40129 Protein, CT4320 Protein, Dmel\\CG40129 Protein, Gprk-1 Protein, Rok Protein, gprk1 Protein, grk1 Protein, zgc:112194 Protein, G protein-coupled receptor kinase 1 Protein, G protein-coupled receptor kinase 1 a Protein, G protein-coupled receptor kinase 1 b Protein, GRK1 Protein, Grk1 Protein, Gprk1 Protein, grk1a Protein, grk1b Protein
- Background
- This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type-2).
- Molecular Weight
- 63.3 kDa
- NCBI Accession
- NP_002920
- Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
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