RNASE1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all RNASE1 Proteins
- RNASE1 (Ribonuclease, RNase A Family, 1 (Pancreatic) (RNASE1))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This RNASE1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human RNASE1 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product RNASE1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- RNASE1 (Ribonuclease, RNase A Family, 1 (Pancreatic) (RNASE1))
- Alternative Name
- Rnase1 (RNASE1 Products)
- Synonyms
- RNASE1 Protein, RNS1 Protein, ATRNS1 Protein, RIBONUCLEASE 1 Protein, T17M13.16 Protein, T17M13_16 Protein, ribonuclease 1 Protein, RIB1 Protein, AI574248 Protein, Rib-1 Protein, Rib1 Protein, SRN Protein, ribonuclease A family member 1, pancreatic Protein, ribonuclease pancreatic-like Protein, ribonuclease A family member k6 Protein, Ribonuclease 1 Protein, ribonuclease 1 Protein, ribonuclease, RNase A family, 1 (pancreatic) Protein, ribonuclease pancreatic Protein, RNASE1 Protein, LOC475395 Protein, RNASE6 Protein, Rnase1 Protein, RNS1 Protein, LOC101113761 Protein
- Background
- This gene encodes a member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. The encoded endonuclease cleaves internal phosphodiester RNA bonds on the 3'-side of pyrimidine bases. It prefers poly(C) as a substrate and hydrolyzes 2',3'-cyclic nucleotides, with a pH optimum near 8.0. The encoded protein is monomeric and more commonly acts to degrade ds-RNA over ss-RNA. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.
- Molecular Weight
- 14.5 kDa
- NCBI Accession
- NP_937878
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