AIMP1 Protein (His tag)

Catalog No. ABIN2731511

Product Details

Target: AIMP1 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This AIMP1 protein is labelled with His tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human SCYE1 / EMAP2 (full length, N-term HIS tag, transcript variant 1) protein expressed in E.coli.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: AIMP1 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))

Alternative Name: Scye1,emap2 (AIMP1 Products)

Synonyms: EMAP2 Protein, EMAPII Protein, HLD3 Protein, SCYE1 Protein, p43 Protein, wu:fa95a05 Protein, zgc:154081 Protein, AIMP1 Protein, 9830137A06Rik Protein, AIMP1/p43 Protein, Emap2 Protein, Scye1 Protein, scye1 Protein, aminoacyl tRNA synthetase complex interacting multifunctional protein 1 Protein, aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 Protein, aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 S homeolog Protein, AIMP1 Protein, aimp1 Protein, Aimp1 Protein, aimp1.S Protein

Background: The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20.

Molecular Weight: 34.2 kDa

NCBI Accession: NP_004748