SETDB1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all SETDB1 Proteins
- SETDB1 (SET Domain, Bifurcated 1 (SETDB1))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SETDB1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human SETDB1 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product SETDB1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- SETDB1 (SET Domain, Bifurcated 1 (SETDB1))
- Alternative Name
- Setdb1 (SETDB1 Products)
- Synonyms
- ESET Protein, H3-K9-HMTase4 Protein, KG1T Protein, KMT1E Protein, TDRD21 Protein, AU022152 Protein, mKIAA0067 Protein, SETDB1 Protein, NV10069 Protein, fc07d03 Protein, si:ch211-81a5.6 Protein, wu:fc07d03 Protein, im:7143091 Protein, wu:fa04a12 Protein, wu:fj80h02 Protein, zgc:152899 Protein, SET domain bifurcated 1 Protein, SET domain, bifurcated 1 Protein, myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11 Protein, histone-lysine N-methyltransferase SETDB1 Protein, SET domain, bifurcated 1a Protein, SET domain bifurcated 1 L homeolog Protein, SET domain, bifurcated 1b Protein, SETDB1 Protein, Setdb1 Protein, MLLT11 Protein, LOC100120014 Protein, LOC100461671 Protein, setdb1a Protein, setdb1.L Protein, setdb1b Protein
- Background
- This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.[provided by RefSeq, Jun 2011].
- Molecular Weight
- 143 kDa
- NCBI Accession
- NP_001138887
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