SH3BP1 Protein (Myc-DYKDDDDK Tag)
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- Target See all SH3BP1 Proteins
- SH3BP1 (SH3-Domain Binding Protein 1 (SH3BP1))
- Protein Type
- Recombinant
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SH3BP1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human SH3BP1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product SH3BP1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- SH3BP1 (SH3-Domain Binding Protein 1 (SH3BP1))
- Alternative Name
- Sh3bp1 (SH3BP1 Products)
- Synonyms
- ARHGAP43 Protein, 3BP-1 Protein, SH3BP1 Protein, SH3 domain binding protein 1 Protein, SH3-domain binding protein 1 Protein, SH3 domain-binding protein 1 Protein, SH3BP1 Protein, Sh3bp1 Protein, LOC100398528 Protein
- Background
- This gene encodes a member of the Rho GTPase activating protein (RhoGAP) family. The encoded protein regulates Rac signaling and plays a role in cytoskeletal dynamics, cell motility and epithelial junction formation. This protein&aposs association with the exocyst complex, which tethers secretory vesicles to the plasma membrane, has been demonstrated to be important in cell motility. In a distinct complex, this protein has been shown to regulate epithelial junction formation and morphogenesis. By interacting with the Plexin-D1 cell surface receptor, this protein mediates changes in the cytoskeleton in response to semaphorin binding. This protein may promote metastasis in human liver cancer cells and tissues.
- Molecular Weight
- 75.5 kDa
- NCBI Accession
- NP_061830
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