SKAP2 Protein (Myc-DYKDDDDK Tag)
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- Target See all SKAP2 Proteins
- SKAP2 (Src Kinase Associated Phosphoprotein 2 (SKAP2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SKAP2 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human SKAP2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product SKAP2 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- SKAP2 (Src Kinase Associated Phosphoprotein 2 (SKAP2))
- Alternative Name
- Skap2 (SKAP2 Products)
- Synonyms
- scap2 Protein, 2610021A10Rik Protein, AA960083 Protein, BB137539 Protein, RA70 Protein, SKAP-HOM Protein, Saps Protein, Scap2 Protein, mSKAP55R Protein, PRAP Protein, SAPS Protein, SCAP2 Protein, SKAP55R Protein, Scap55r Protein, SKAP55 Protein, si:dz227h09.6 Protein, si:dz31b14.4 Protein, zgc:158223 Protein, zgc:65975 Protein, src kinase associated phosphoprotein 2 L homeolog Protein, SRC kinase associated phosphoprotein 2 Protein, src family associated phosphoprotein 2 Protein, src kinase associated phosphoprotein 2 Protein, skap2.L Protein, CCC13826_0176 Protein, Skap2 Protein, SKAP2 Protein, skap2 Protein
- Background
- The protein encoded by this gene shares homology with Src kinase-associated phosphoprotein 1, and is a substrate of Src family kinases. It is an adaptor protein that is thought to play an essential role in the Src signaling pathway, and in regulating proper activation of the immune system. This protein contains an amino terminal coiled-coil domain for self-dimerization, a plecskstrin homology (PH) domain required for interactions with lipids at the membrane, and a Src homology (SH3) domain at the carboxy terminus. Some reports indicate that this protein inhibits actin polymerization through interactions with actin assembly factors, and might negatively regulate the invasiveness of tumors by modulating actin assembly. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Molecular Weight
- 41 kDa
- NCBI Accession
- NP_003921
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