SMARCE1 Protein (Myc-DYKDDDDK Tag)
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- Target See all SMARCE1 Proteins
- SMARCE1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily E, Member 1 (SMARCE1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SMARCE1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human SMARCE1 / BAF57 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product SMARCE1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- SMARCE1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily E, Member 1 (SMARCE1))
- Alternative Name
- Smarce1,baf57 (SMARCE1 Products)
- Synonyms
- BAF57 Protein, XBaf57 Protein, MGC52696 Protein, MGC69429 Protein, MGC81726 Protein, SMARCE1 Protein, DKFZp459O2235 Protein, fb54d11 Protein, wu:fb33d02 Protein, wu:fb54d11 Protein, Baf57 Protein, 2810417B20Rik Protein, 5830412H02Rik Protein, 9030408N19Rik Protein, Baf27 Protein, RGD1304726 Protein, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 Protein, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 L homeolog Protein, smarce1 Protein, SMARCE1 Protein, smarce1.L Protein, Smarce1 Protein
- Background
- The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart.
- Molecular Weight
- 46.5 kDa
- NCBI Accession
- NP_003070
- Pathways
- Chromatin Binding
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