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SNAPIN Protein (Myc-DYKDDDDK Tag)

SNAPIN Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2732314
  • Target See all SNAPIN Proteins
    SNAPIN (SNAP-Associated Protein (SNAPIN))
    Protein Type
    Recombinant
    Origin
    • 4
    • 1
    • 1
    Human
    Source
    • 3
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This SNAPIN protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human SNAPIN protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
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    Discover our top product SNAPIN Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    SNAPIN (SNAP-Associated Protein (SNAPIN))
    Alternative Name
    Snapin (SNAPIN Products)
    Synonyms
    SNAPAP Protein, si:dkey-222b8.2 Protein, SNAPIN Protein, BLOC1S7 Protein, BLOS7 Protein, 25kDa Protein, AA407989 Protein, AV026596 Protein, Bloc1s7 Protein, Snap25bp Protein, Snapap Protein, SNAP associated protein Protein, SNAP-associated protein L homeolog Protein, SNAP-associated protein Protein, SNAPIN Protein, snapin.L Protein, snapin Protein, Snapin Protein
    Background
    The protein encoded by this gene is a coiled-coil-forming protein that associates with the SNARE (soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor) complex of proteins and the BLOC-1 (biogenesis of lysosome-related organelles) complex. Biochemical studies have identified additional binding partners. As part of the SNARE complex, it is required for vesicle docking and fusion and regulates neurotransmitter release. The BLOC-1 complex is required for the biogenesis of specialized organelles such as melanosomes and platelet dense granules. Mutations in gene products that form the BLOC-1 complex have been identified in mouse strains that are models of Hermansky-Pudlak syndrome. Alternative splicing results in multiple transcript variants.
    Molecular Weight
    14.7 kDa
    NCBI Accession
    NP_036569
    Pathways
    Synaptic Membrane, Synaptic Vesicle Exocytosis
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