Sorbs2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all Sorbs2 Proteins
- Sorbs2 (Sorbin and SH3 Domain Containing 2 (Sorbs2))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Sorbs2 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Sorbin and SH3 domain containing 2 (SORBS2), transcript variant 1 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product Sorbs2 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- Sorbs2 (Sorbin and SH3 Domain Containing 2 (Sorbs2))
- Abstract
- Sorbs2 Products
- Synonyms
- Argbp2 Protein, 2010203O03Rik Protein, 9430041O17Rik Protein, A530071H08 Protein, mKIAA0777 Protein, argbp2 Protein, pro0618 Protein, 9430041O17RIK Protein, DKFZp468F1119 Protein, ARGBP2 Protein, PRO0618 Protein, sorbin and SH3 domain containing 2 Protein, Sorbs2 Protein, SORBS2 Protein, sorbs2 Protein
- Background
- Arg and c-Abl represent the mammalian members of the Abelson family of non-receptor protein-tyrosine kinases. They interact with the Arg/Abl binding proteins via the SH3 domains present in the carboxy end of the latter group of proteins. This gene encodes the sorbin and SH3 domain containing 2 protein. It has three C-terminal SH3 domains and an N-terminal sorbin homology (SoHo) domain that interacts with lipid raft proteins. The subcellular localization of this protein in epithelial and cardiac muscle cells suggests that it functions as an adapter protein to assemble signaling complexes in stress fibers, and that it is a potential link between Abl family kinases and the actin cytoskeleton. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Molecular Weight
- 69.8 kDa
- NCBI Accession
- NP_003594
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