SNX15 Protein (Transcript Variant A) (Myc-DYKDDDDK Tag)
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- Target See all SNX15 Proteins
- SNX15 (Sorting Nexin 15 (SNX15))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant A
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SNX15 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Sorting nexin-15 (SNX15) (transcript variant A) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product SNX15 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- SNX15 (Sorting Nexin 15 (SNX15))
- Alternative Name
- Sorting Nexin-15 (Snx15) (SNX15 Products)
- Synonyms
- SNX15 Protein, hsaf001435 Protein, snx15 Protein, MGC154249 Protein, HSAF001435 Protein, 1500032B08Rik Protein, E130013C21Rik Protein, sorting nexin 15 Protein, sorting nexin 15 S homeolog Protein, SNX15 Protein, snx15.S Protein, snx15 Protein, Snx15 Protein
- Background
- This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ADP-ribosylation factor-like 2 (ARL2) gene.
- Molecular Weight
- 38.1 kDa
- NCBI Accession
- NP_037438
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