TMSB4X Protein
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- Target See all TMSB4X Proteins
- TMSB4X (Thymosin beta-4 (TMSB4X))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- Functional Studies (Func), Antibody Production (AbP), Standard (STD), Protein Interaction (PI)
- Specificity
- Optimal preservation of protein structure, post-translational modifications and functions.
- Characteristics
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- Recombinant human Thymosin beta-4 protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Tested for bioactivity.
- Purity
- > 95 % as determined by SDS-PAGE and Coomassie blue staining
- Endotoxin Level
- Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
- Biological Activity Comment
- Pretreatment of primary lung fibroblasts with recombinant Thymosin-beta4, using a concentration of 0.5 - 10 ug/mL, produces a protective effect against hydrogen peroxide induced cell death.
- Top Product
- Discover our top product TMSB4X Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays - Restrictions
- For Research Use only
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- Buffer
- Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
- Handling Advice
- Resuspend the protein in the desired concentration in proper buffer
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- TMSB4X (Thymosin beta-4 (TMSB4X))
- Alternative Name
- Thymosin beta-4 (TMSB4X Products)
- Synonyms
- FX Protein, PTMB4 Protein, TB4X Protein, TMSB4 Protein, Ptmb4 Protein, Tb4 Protein, tmsb4 Protein, TMSB4X Protein, thymosin beta 4, X-linked Protein, thymosin, beta 4, X chromosome Protein, thymosin beta 4, X-linked L homeolog Protein, thymosin, beta 4-like Protein, thymosin beta 4 pseudogene Protein, TMSB4X Protein, Tmsb4x Protein, tmsb4x.L Protein, TMSB4 Protein, LOC100339394 Protein, LOC100860922 Protein
- Background
- This gene encodes an actin sequestering protein which plays a role in regulation of actin polymerization. The protein is also involved in cell proliferation, migration, and differentiation. This gene escapes X inactivation and has a homolog on chromosome Y.
- Molecular Weight
- 5.2 kDa
- NCBI Accession
- NP_066932
- Pathways
- Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Maintenance of Protein Location, Smooth Muscle Cell Migration
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