TJP3 Protein (Myc-DYKDDDDK Tag)
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- Target See all TJP3 Proteins
- TJP3 (Tight Junction Protein 3 (Zona Occludens 3) (TJP3))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TJP3 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Tight junction protein 3 (zona occludens 3) (TJP3) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product TJP3 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- TJP3 (Tight Junction Protein 3 (Zona Occludens 3) (TJP3))
- Abstract
- TJP3 Products
- Synonyms
- cb766 Protein, wu:fj93c08 Protein, zo-3 Protein, zo3 Protein, ZO-3 Protein, ZO3 Protein, tight junction protein 3 Protein, tight junction protein 3 S homeolog Protein, tjp3 Protein, tjp3.S Protein, TJP3 Protein, Tjp3 Protein
- Background
- The protein encoded by this gene is a member of the membrane-associated guanylate kinase-like (MAGUK) protein family which is characterized by members having multiple PDZ domains, a single SH3 domain, and a single guanylate kinase-like (GUK)-domain. In addition, members of the zonula occludens protein subfamily have an acidic domain, a basic arginine-rich region, and a proline-rich domain. The protein encoded by this gene plays a role in the linkage between the actin cytoskeleton and tight-junctions and also sequesters cyclin D1 at tight junctions during mitosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. This gene has a partial pseudogene on chromosome 1.
- Molecular Weight
- 104.6 kDa
- NCBI Accession
- NP_055243
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