TCOF1 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)
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- Target See all TCOF1 Proteins
- TCOF1 (Treacher Collins-Franceschetti Syndrome 1 (TCOF1))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 3
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TCOF1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Treacle protein / TCOF1 (transcript variant 3) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product TCOF1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- TCOF1 (Treacher Collins-Franceschetti Syndrome 1 (TCOF1))
- Alternative Name
- Treacle Protein,tcof1 (TCOF1 Products)
- Synonyms
- TCOF1 Protein, AA408847 Protein, AW209012 Protein, treacle Protein, MFD1 Protein, TCS1 Protein, treacle ribosome biogenesis factor 1 Protein, Tcof1 Protein, TCOF1 Protein
- Background
- This gene encodes a nucleolar protein with a LIS1 homology domain. The protein is involved in ribosomal DNA gene transcription through its interaction with upstream binding factor (UBF). Mutations in this gene have been associated with Treacher Collins syndrome, a disorder which includes abnormal craniofacial development. Multiple transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
- 96.6 kDa
- NCBI Accession
- NP_001008657
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