UBA3 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all UBA3 Proteins
- UBA3 (Ubiquitin-Like Modifier Activating Enzyme 3 (UBA3))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This UBA3 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human UBA3 / UBE1C (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product UBA3 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- UBA3 (Ubiquitin-Like Modifier Activating Enzyme 3 (UBA3))
- Alternative Name
- Uba3,ube1c (UBA3 Products)
- Synonyms
- UBE1C Protein, hUBA3 Protein, Ube1c Protein, ube1c Protein, wu:fb75e04 Protein, wu:fc37b11 Protein, zgc:55528 Protein, A830034N06Rik Protein, AI256736 Protein, AI848246 Protein, AW546539 Protein, ubiquitin like modifier activating enzyme 3 Protein, ubiquitin-like modifier activating enzyme 3 Protein, ubiquitin like modifier activating enzyme 3 S homeolog Protein, UBA3 Protein, Uba3 Protein, uba3 Protein, uba3.S Protein
- Background
- The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
- Molecular Weight
- 51.7 kDa
- NCBI Accession
- NP_003959
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