UGT1A10 Protein (Myc-DYKDDDDK Tag)
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- Target See all UGT1A10 Proteins
- UGT1A10 (UDP Glucuronosyltransferase 1 Family, Polypeptide A10 (UGT1A10))
- Protein Type
- Recombinant
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This UGT1A10 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human UGT1A10 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product UGT1A10 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- UGT1A10 (UDP Glucuronosyltransferase 1 Family, Polypeptide A10 (UGT1A10))
- Alternative Name
- Ugt1a10 (UGT1A10 Products)
- Synonyms
- UDPGT Protein, UGT-1J Protein, UGT1-10 Protein, UGT1.10 Protein, UGT1J Protein, A13 Protein, Ugt1a13 Protein, UDP glucuronosyltransferase family 1 member A10 Protein, UDP glycosyltransferase 1 family, polypeptide A10 Protein, UGT1A10 Protein, Ugt1a10 Protein
- Background
- This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5&apos exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene has glucuronidase activity on mycophenolic acid, coumarins, and quinolines.
- Molecular Weight
- 57.2 kDa
- NCBI Accession
- NP_061948
- Pathways
- Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha
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