VPREB3 Protein (Myc-DYKDDDDK Tag)
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- Target See all VPREB3 Proteins
- VPREB3 (Pre-B Lymphocyte 3 (VPREB3))
- Protein Type
- Recombinant
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This VPREB3 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human VPREB3 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product VPREB3 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- VPREB3 (Pre-B Lymphocyte 3 (VPREB3))
- Alternative Name
- Vpreb3 (VPREB3 Products)
- Synonyms
- 8HS-20 Protein, Vpreb-3 Protein, AI528709 Protein, VPREB3 Protein, 8HS20 Protein, N27C7-2 Protein, pre-B lymphocyte gene 3 Protein, V-set pre-B cell surrogate light chain 3 Protein, pre-B lymphocyte 3 Protein, Ig lambda-6 chain C region Protein, Vpreb3 Protein, VPREB3 Protein, LOC698694 Protein
- Background
- The protein encoded by this gene is the human ortholog of the mouse VpreB3 (8HS20) protein, is thought to be involved in B-cell maturation, and may play a role in assembly of the pre-B cell receptor (pre-BCR). While the role of this protein in B-cell development has not yet been elucidated, studies with the chicken ortholog of this protein have found that when overexpressed, this protein localizes to the endoplasmic reticulum. The mouse ortholog of this protein has been shown to associate with membrane mu heavy chains early in the course of pre-B cell receptor biosynthesis. Expression of this gene has been observed in some lymphomas.
- Molecular Weight
- 13.5 kDa
- NCBI Accession
- NP_037510
- Pathways
- Production of Molecular Mediator of Immune Response
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