DEFB103A Protein
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- Target See all DEFB103A Proteins
- DEFB103A (Defensin, beta 103A (DEFB103A))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- Functional Studies (Func)
- Sequence
- GIINTLQKYY CRVRGGRCAV LSCLPKEEQI GKCSTRGRKC CRRKK
- Characteristics
- Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by anti-microbial activity against E.coli. is less than 30 μg/mL, corresponding to a specific activity of > 33.3 IU/mg.
- Purity
- >98 % as determined by SDS-PAGE and HPLC.
- Sterility
- 0.2 μm filtered
- Top Product
- Discover our top product DEFB103A Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 20 mM PB, pH 7.4, 130 mM NaCl
- Storage
- -20 °C
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- Target
- DEFB103A (Defensin, beta 103A (DEFB103A))
- Alternative Name
- DEFB103A (DEFB103A Products)
- Synonyms
- BD-3 Protein, DEFB-3 Protein, DEFB103 Protein, DEFB3 Protein, HBD3 Protein, HBP-3 Protein, HBP3 Protein, hBD-3 Protein, DEFB103B Protein, defensin beta 103A Protein, defensin beta 103B Protein, defensin, beta 103A Protein, beta-defensin 103 Protein, DEFB103A Protein, DEFB103B Protein, LOC694235 Protein, LOC100359096 Protein
- Background
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Relevance: Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed. {ECO:0000269|PubMed:11085990}.
Synonyms: Beta-defensin 3, DEFB-3, HBD3, hBD-3, Defensin, beta 103 - Molecular Weight
- 5.2 kDa
- UniProt
- P81534
- Pathways
- Production of Molecular Mediator of Immune Response
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