RAB1A Protein (AA 2-205) (GST tag)

Catalog No. ABIN4975537

Product Details

Target: RAB1A (RAB1A, Member RAS Oncogene Family (RAB1A))

Protein Type: Recombinant

Protein Characteristics: AA 2-205

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This RAB1A protein is labelled with GST tag.

Application: SDS-PAGE (SDS)

Sequence: SSMNPEYDYL FKLLLIGDSG VGKSCLLLRF ADDTYTESYI STIGVDFKIR TIELDGKTIK LQIWDTAGQE RFRTITSSYY RGAHGIIVVY DVTDQESFNN VKQWLQEIDR YASENVNKLL VGNKCDLTTK KVVDYTTAKE FADSLGIPFL ETSAKNATNV EQSFMTMAAE IKKRMGPGAT AGGAEKSNVK IQSTPVKQSG GGCC

Purification: SDS-PAGE

Purity: > 90 %

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Storage: -80 °C,4 °C,-20 °C

Storage Comment: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Target Details

Target: RAB1A (RAB1A, Member RAS Oncogene Family (RAB1A))

Alternative Name: RAB1A (RAB1A Products)

Synonyms: RAB1 Protein, YPT1 Protein, RAS Protein, RAB1B Protein, fb53a02 Protein, oncogene Protein, wu:fb53a02 Protein, si:zc101n13.3 Protein, rab1 Protein, MGC53138 Protein, RAB1A Protein, AAF55873 Protein, CG3320 Protein, DRAB1 Protein, DRab1 Protein, Dm Rab1 Protein, DmRab1 Protein, Dmel\\CG3320 Protein, RAB1a Protein, Rab1a Protein, dRab1 Protein, dar6 Protein, drab1 Protein, DDBDRAFT_0185730 Protein, DDBDRAFT_0191476 Protein, DDB_0185730 Protein, DDB_0191476 Protein, Gtbp Protein, Rab-1 Protein, Rab1A Protein, Ypt1 Protein, mKIAA3012 Protein, Ac2-048 Protein, Rab1 Protein, Rab1r Protein, RAB1A, member RAS oncogene family Protein, RAB1A, member RAS oncogene family b Protein, RAB1A, member RAS oncogene family L homeolog Protein, RAB1B, member RAS oncogene family Protein, CG3320 gene product from transcript CG3320-RA Protein, rab1A protein Protein, PfRab1a Protein, hypothetical protein Protein, Rab GTPase Protein, angiogenin Protein, RAB1A Protein, rab1ab Protein, rab1a.L Protein, RAB1B Protein, rab1a Protein, Rab1 Protein, rab1A Protein, Rab1a Protein, ANG Protein

Background: The small GTPases Rab are key regulators of intracellular mbrane trafficking, from the formation of transport vesicles to their fusion with mbranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to mbranes different sets of downstream effectors directly responsible for vesicle formation, movent, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secretion. Regulates the level of CASR present at the cell mbrane. Plays a role in cell adhesion and cell migration, via its role in protein trafficking. Plays a role in autophagosome assbly and cellular defense reactions against pathogenic bacteria. Plays a role in microtubule-dependent protein transport by early endosomes and in anterograde melanosome transport.

Molecular Weight: 49.9 kDa

UniProt: P62820

Pathways: SARS-CoV-2 Protein Interactome