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Frataxin Protein (FXN) (AA 81-210) (His tag)

FXN Origin: Cynomolgus Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Catalog No. ABIN4976693
  • Target See all Frataxin (FXN) Proteins
    Frataxin (FXN)
    Protein Type
    Recombinant
    Protein Characteristics
    AA 81-210
    Origin
    • 10
    • 4
    • 2
    • 1
    Cynomolgus
    Source
    • 10
    • 3
    • 2
    • 2
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This Frataxin protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    SGTLGHPGSL DDTTYERLAE ETLDSLAEFF EDLADKPYTF EDYDVSFGSG VLTVKLGGDL GTYVINKQTP NKQIWLSSPS SGPKRYDRTG KNWVYSHDGV SLHELLGAEL TKALKTKLDL SSLAYSGKDA
    Purification
    SDS-PAGE
    Purity
    > 90 %
    Top Product
    Discover our top product FXN Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Storage
    -80 °C,4 °C,-20 °C
    Storage Comment
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Target
    Frataxin (FXN)
    Alternative Name
    FRDA (FXN Products)
    Synonyms
    zgc:158218 Protein, LOC100284365 Protein, BcDNA:AT09528 Protein, CG8971 Protein, DFH Protein, Dfh Protein, Dmel\\CG8971 Protein, X25 Protein, dfh Protein, CyaY Protein, FA Protein, FARR Protein, FRDA Protein, RGD1565754 Protein, Frda Protein, frataxin Protein, fxn Protein, LOC100284365 Protein, TVAG_182150 Protein, fh Protein, FTX1 Protein, FXN Protein, Fxn Protein
    Background
    Promotes the biosynthesis of he and assbly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+, the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. Modulates the RNA-binding activity of ACO1 .
    Molecular Weight
    18.3 kDa
    UniProt
    Q8HXX9
    Pathways
    Transition Metal Ion Homeostasis, Regulation of Cell Size
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