GLRa2 Protein (AA 27-143, Extracellular) (GST tag)
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- Target See all GLRa2 Proteins
- GLRa2 (Glycine Receptor, alpha 2 (GLRa2))
- Protein Type
- Recombinant
- Protein Characteristics
- Extracellular, AA 27-143
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Origin
- Mouse
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This GLRa2 protein is labelled with GST tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- AQVMDFLFEK WKLYSDQCHH NLSLLPPPTE LVCNRTFDKY SCWPDTPPNT TANISCPWYL PWYHKVQHRL VFKRCGPDGQ WVRGPRGQPW RNASQCQLDD EEIEVQKGVA KMYSSQQ
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product GLRa2 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- GLRa2 (Glycine Receptor, alpha 2 (GLRa2))
- Alternative Name
- GLR (GLRa2 Products)
- Synonyms
- GLR Protein, RNNEOGLY Protein, glycine receptor alpha 2 Protein, glycine receptor, alpha 2 Protein, glycine receptor, alpha 2 subunit Protein, GLRA2 Protein, Glra2 Protein, glra2 Protein
- Background
- G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger syst.
- Molecular Weight
- 41.2 kDa
- UniProt
- Q61606
- Pathways
- Synaptic Membrane
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