CYR61 Protein (AA 25-379) (His tag)
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- Target See all CYR61 Proteins
- CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 25-379
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Origin
- Mouse
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Source
- Yeast
- Purification tag / Conjugate
- This CYR61 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- TCPAACHCPL EAPKCAPGVG LVRDGCGCCK VCAKQLNEDC SKTQPCDHTK GLECNFGASS TALKGICRAQ SEGRPCEYNS RIYQNGESFQ PNCKHQCTCI DGAVGCIPLC PQELSLPNLG CPNPRLVKVS GQCCEEWVCD EDSIKDSLDD QDDLLGLDAS EVELTRNNEL IAIGKGSSLK RLPVFGTEPR VLFNPLHAHG QKCIVQTTSW SQCSKSCGTG ISTRVTNDNP ECRLVKETRI CEVRPCGQPV YSSLKKGKKC SKTKKSPEPV RFTYAGCSSV KKYRPKYCGS CVDGRCCTPL QTRTVKMRFR CEDGEMFSKN VMMIQSCKCN YNCPHPNEAS FRLYSLFNDI HKFRD
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product CYR61 Protein
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Cysteine-Rich, Angiogenic Inducer, 61 (CYR61) (AA 1-381) protein (GST tag)
CYR61 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Cysteine-Rich, Angiogenic Inducer, 61 (CYR61) (AA 25-381) protein (His tag)CYR61 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Cysteine-Rich, Angiogenic Inducer, 61 (CYR61) (AA 293-381) protein (GST tag)CYR61 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Cysteine-Rich, Angiogenic Inducer, 61 (CYR61) (AA 25-381) protein (GST tag)CYR61 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Cysteine-Rich, Angiogenic Inducer, 61 (CYR61) (AA 25-381) protein (His tag)Crystallography grade CYR61 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Cysteine-Rich, Angiogenic Inducer, 61 (CYR61) (AA 25-379) protein (His tag)Crystallography grade CYR61 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))
- Alternative Name
- CYR61 (CYR61 Products)
- Synonyms
- CCN1 Protein, GIG1 Protein, IGFBP10 Protein, ccn1 Protein, gig1 Protein, Xcyr61 Protein, igfbp10 Protein, MGC69281 Protein, MGC69539 Protein, cyr61-l2 Protein, zgc:158158 Protein, CYR61 Protein, AI325051 Protein, Igfbp10 Protein, cysteine rich angiogenic inducer 61 Protein, cysteine-rich, angiogenic inducer, 61 Protein, cysteine-rich, angiogenic inducer, 61 like 2 Protein, cysteine rich protein 61 Protein, cysteine rich angiogenic inducer 61 S homeolog Protein, CYR61 Protein, Cyr61 Protein, cyr61 Protein, cyr61l2 Protein, cyr61.S Protein
- Background
- Promotes cell proliferation, chotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix rodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5 . CYR61-mediated gene regulation is dependent on heparin-binding . Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1 . Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-1/beta-5 and cell proliferation through integrin alpha-v/beta-3 .
- Molecular Weight
- 41.14 kDa
- UniProt
- P18406
- Pathways
- Positive Regulation of Endopeptidase Activity, Growth Factor Binding
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