MCCC1 Protein (His tag)
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- Target See all MCCC1 Proteins
- MCCC1 (Methylcrotonoyl-CoA Carboxylase 1 (Alpha) (MCCC1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This MCCC1 protein is labelled with His tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Purified recombinant protein of Human methylcrotonoyl-CoA carboxylase 1 (alpha) (MCCC1), nuclear gene encoding mitochondrial protein, full length, with N-terminal HIS tag, expressed in E. coli, 50 μg (full length, N-term HIS tag) protein expressed in E.coli.
- Produced with end-sequenced ORF clone
- Purification
- Purified
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product MCCC1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the N-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- MCCC1 (Methylcrotonoyl-CoA Carboxylase 1 (Alpha) (MCCC1))
- Alternative Name
- MCCC1 (MCCC1 Products)
- Synonyms
- MCC-B Protein, MCCA Protein, 1810045E08Rik Protein, 2310058B18Rik Protein, MCCalpha Protein, Mcca Protein, R75106 Protein, methylcrotonoyl-CoA carboxylase 1 Protein, methylcrotonyl-CoA carboxylase alpha chain Protein, methylcrotonoyl-Coenzyme A carboxylase 1 (alpha) Protein, MCCC1 Protein, Mccc1 Protein, MCCA Protein
- Background
- This gene encodes the large subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism.
- Molecular Weight
- 75.6 kDa
- NCBI Accession
- NP_064551
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