LILRB5 Protein (AA 24-458) (Fc Tag,AVI tag,Biotin)
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- Target See all LILRB5 Proteins
- LILRB5 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 5 (LILRB5))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 24-458
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This LILRB5 protein is labelled with Fc Tag,AVI tag,Biotin.
- Brand
- PrecisionAvi
- Sequence
- AA 24-458
- Specificity
- Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
- Characteristics
- This protein carries a human IgG1 Fc tag at the C-terminus, followed by a Avi tag (Avitag™). The protein has a calculated MW of 75.8 kDa. The protein migrates as 90-105 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product LILRB5 Protein
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- Comment
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Ready-to-use AvitagTM biotinylated protein:
The product is exclusively produced using the AvitagTM technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.
This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled. - Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Tris with Glycine, Arginine and NaCl, pH 7.5
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
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- Target
- LILRB5 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 5 (LILRB5))
- Alternative Name
- LILRB5 (LILRB5 Products)
- Synonyms
- LILRB5 Protein, CD85C Protein, LIR-8 Protein, LIR8 Protein, leukocyte immunoglobulin-like receptor subfamily B member 5 Protein, leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5 Protein, leukocyte immunoglobulin like receptor B5 Protein, LOC695256 Protein, LILRB5 Protein
- Background
- Leukocyte immunoglobulin-like receptor subfamily B member 5 (LILRB5), also known as CD85c and LIR-8, belongs to the leukocyte immunoglobulin-like receptor (LIR) family of transmembrane glycoproteins that negatively regulate immune cell activation. Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response.
- Molecular Weight
- 75.8 kDa
- NCBI Accession
- NP_006831
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