PSMF1 Protein (AA 1-271) (His tag)
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- Target See all PSMF1 Proteins
- PSMF1 (Proteasome (Prosome, Macropain) Inhibitor Subunit 1 (PI31) (PSMF1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-271
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PSMF1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- PSMF1, 1-271aa , Human, His tag E.coli
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product PSMF1 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 1mM DTT,0.1mM PMSF
- Storage
- 4 °C
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- Target
- PSMF1 (Proteasome (Prosome, Macropain) Inhibitor Subunit 1 (PI31) (PSMF1))
- Alternative Name
- PSMF1 (PSMF1 Products)
- Synonyms
- PI31 Protein, AW048666 Protein, BC012260 Protein, zgc:92785 Protein, proteasome inhibitor subunit 1 Protein, proteasome (prosome, macropain) inhibitor subunit 1 Protein, PSMF1 Protein, Psmf1 Protein, psmf1 Protein
- Background
- PSMF1 is a protein that inhibits the activation of the proteasome by the 11S and 19S regulators. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Recombinant human PSMF1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Proteasome inhibitor subunit 1 isoform 1, PI31. NCBI no.: NP_006805
- Molecular Weight
- 31.9 kDa (291aa), confirmed by MALDI-TOF
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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