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OAS1 Protein (AA 1-364) (His tag)

OAS1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS-PAGE SDS
Catalog No. ABIN666789
  • Target See all OAS1 Proteins
    OAS1 (2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-364
    Origin
    • 6
    • 2
    • 1
    • 1
    Human
    Source
    • 5
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This OAS1 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    OAS1, 1-364 aa, Human, His-tagged, Recombinant, E.coli
    Purity
    > 95 % by SDS-PAGE
    Top Product
    Discover our top product OAS1 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol and 1mM DTT.
    Storage
    4 °C
  • Target
    OAS1 (2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1))
    Alternative Name
    OAS1 (OAS1 Products)
    Synonyms
    OAS1 Protein, IFI-4 Protein, OIAS Protein, OIASI Protein, L3 Protein, Pp2a2 Protein, 2',5'-oligoadenylate synthetase 1 Protein, 2'-5'-oligoadenylate synthetase 1 Protein, 2'-5' oligoadenylate synthetase 1A Protein, protein phosphatase 2 catalytic subunit beta Protein, OAS1 Protein, Oas1a Protein, Ppp2cb Protein, Oas1 Protein
    Background
    OAS1 is an enzyme included in the 2’,5’-oligoadenylate synthase family. This enzyme is induced by interferons and uses adenosine triphosphate in 2’-specific nucleotidyl transfer reactions to synthesize 2’,5’-oligoadenylates(2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. OAS1 may play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis. Recombinant OAS1 protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: IFI-4, OIAS, OIASI, 2’,5’-oligoadenylate synthetase 1, isoform2 (2 5')oligo(A) synthetase 1, 2' 5' oligo A synthetase 1, 2 5 Oligoadenylate Synthetase 1, 2 5A synthetase 1, 2' 5' oligoadenylate synthetase 1, 2' 5' oligoisoadenylate synthetase 1, 2'5' oligoadenylate synthetase 1, 2'5' oligoisoadenylate synthetase 1, p46/p42 OAS, 2'5' oligo A synthetase 1, E18/E16, IFI 4, IFI4, OAS 1,. NCBI no.: NP_002525
    Molecular Weight
    43.9 kDa (384aa), confirmed by MALDI-TOF.
    Pathways
    Hepatitis C
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