OAS1 Protein (AA 1-400) (GST tag)
(1 reference)-
- Target See all OAS1 Proteins
- OAS1 (2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-400
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Origin
- Human
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Source
- Wheat germ
- Purification tag / Conjugate
- This OAS1 protein is labelled with GST tag.
- Application
- Western Blotting (WB), ELISA, Affinity Purification (AP), Antibody Array (AA)
- Purpose
- OAS1 (Human) Recombinant Protein (P01)
- Sequence
- MMDLRNTPAK SLDKFIEDYL LPDTCFRMQI NHAIDIICGF LKERCFRGSS YPVCVSKVVK GGSSGKGTTL RGRSDADLVV FLSPLTTFQD QLNRRGEFIQ EIRRQLEACQ RERAFSVKFE VQAPRWGNPR ALSFVLSSLQ LGEGVEFDVL PAFDALGQLT GGYKPNPQIY VKLIEECTDL QKEGEFSTCF TELQRDFLKQ RPTKLKSLIR LVKHWYQNCK KKLGKLPPQY ALELLTVYAW ERGSMKTHFN TAQGFRTVLE LVINYQQLCI YWTKYYDFKN PIIEKYLRRQ LTKPRPVILD PADPTGNLGG GDPKGWRQLA QEAEAWLNYP CFKNWDGSPV SSWILLAESN SADDETDDPR RYQKYGYIGT HEYPHFSHRP STLQAASTPQ AEEDWTCTIL
- Characteristics
- Human OAS1 full-length ORF ( NP_058132.2, 1 a.a. - 400 a.a.) recombinant protein with GST-tag at N-terminal.
- Purification
- in vitro wheat germ expression system
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2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 1-364) protein (His tag)
OAS1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 1-100) protein (GST tag)OAS1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 1-400) protein (Strep Tag)Crystallography grade OAS1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)OAS1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Preparation method: in vitro, wheat germ expression system
Product Quality tested by: 12.5% SDS-PAGE Stained with Coomassie Blue. - Restrictions
- For Research Use only
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- Buffer
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.
- Handling Advice
- Aliquot to avoid repeated freezing and thawing.
- Storage
- -80 °C
- Storage Comment
- Best use within three months from the date of receipt of this protein.
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: "The association of elevated 2',5'-oligoadenylate-dependent RNase L with lung cancer correlated with deficient enzymatic activity and decreased capacity of RNase L dimerization." in: Lung cancer (Amsterdam, Netherlands), Vol. 78, Issue 1, pp. 30-8, (2012) (PubMed).
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: "The association of elevated 2',5'-oligoadenylate-dependent RNase L with lung cancer correlated with deficient enzymatic activity and decreased capacity of RNase L dimerization." in: Lung cancer (Amsterdam, Netherlands), Vol. 78, Issue 1, pp. 30-8, (2012) (PubMed).
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- Target
- OAS1 (2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1))
- Alternative Name
- OAS1 (OAS1 Products)
- Synonyms
- OAS1 Protein, IFI-4 Protein, OIAS Protein, OIASI Protein, L3 Protein, Pp2a2 Protein, 2',5'-oligoadenylate synthetase 1 Protein, 2'-5'-oligoadenylate synthetase 1 Protein, 2'-5' oligoadenylate synthetase 1A Protein, protein phosphatase 2 catalytic subunit beta Protein, OAS1 Protein, Oas1a Protein, Ppp2cb Protein, Oas1 Protein
- Background
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Full Gene Name: 2',5'-oligoadenylate synthetase 1, 40/46 kDa
Synonyms: IFI-4,OIAS,OIASI - Gene ID
- 4938
- NCBI Accession
- NM_016816
- Pathways
- Hepatitis C
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