APRT Protein (AA 1-180)

Catalog No. ABIN666946

Product Details

Target: APRT (Adenine Phosphoribosyltransferase (APRT))

Protein Type: Recombinant

Protein Characteristics: AA 1-180

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Characteristics: APRT, 1-180aa, Human, E.coli

Purity: > 90 % by SDS - PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 10% glycerol

Storage: 4 °C

Target Details

Target: APRT (Adenine Phosphoribosyltransferase (APRT))

Alternative Name: APRT (APRT Products)

Synonyms: Tb07.43M14.200 Protein, Tb07.43M14.180 Protein, C85684 Protein, AMP Protein, APRTD Protein, adenine phosphoribosyltransferase Protein, adenine phosphoribosyl transferase Protein, CND05020 Protein, Tb927.7.1790 Protein, Tb927.7.1780 Protein, Arnit_0941 Protein, Saut_1231 Protein, Fbal_1180 Protein, PH_RS07970 Protein, PF_RS08760 Protein, PAB_RS02560 Protein, Aprt Protein, APRT Protein

Background: APRT (adenine phosphoribosyltransferase) is a 180 amino acid protein that localizes to the cytoplasm and belongs to the purine/pyrimidine phosphoribosyltransferase family. Existing as a homodimer, APRT functions to catalyze the formation of inorganic pyrophosphate and AMP from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP), a reaction that is essential for both purine metabolism and AMP biosynthesis. It also produces adenine as a by-product of the polyamine biosynthesis pathway. Recombinant human APRT protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: AMP, Adenine phosphoribosyltransferase AMP diphosphorylase, AMP pyrophosphorylase, DKFZp686D13177, MGC125856, MGC125857, MGC129961, Transphosphoribosidase. NCBI no.: NP_000476

Molecular Weight: 19.6 kDa (180aa), confirmed by MALDI-TOF.

Pathways: Ribonucleoside Biosynthetic Process