RRM2 Protein (AA 1-389) (His tag)
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- Target See all RRM2 Proteins
- RRM2 (Ribonucleotide Reductase M2 (RRM2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-389
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This RRM2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- RRM2, 1-389aa, Human, His tag, E.coli
- Purity
- > 85 % by SDS - PAGE
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.1M NaCl
- Storage
- 4 °C
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- Target
- RRM2 (Ribonucleotide Reductase M2 (RRM2))
- Alternative Name
- RRM2 (RRM2 Products)
- Synonyms
- R2 Protein, RR2 Protein, RR2M Protein, AA407299 Protein, rrm2 Protein, rr2m Protein, cb111 Protein, chunp6884 Protein, r2 Protein, ribonucleotide reductase regulatory subunit M2 Protein, ribonucleotide reductase M2 Protein, ribonucleotide reductase M2, gene 2 L homeolog Protein, ribonucleotide reductase M2, gene 1 Protein, ribonucleotide reductase M2 polypeptide Protein, RRM2 Protein, Rrm2 Protein, rrm2.2.L Protein, rrm2.1 Protein, rrm2 Protein
- Background
- RRM2, also known as ribonucleotide reductase M2, is an enzyme that catalyzes the formation of deoxyribonucleotides from ribonucleotides. This protein plays a critical role in regulating the total rate of DNA synthesis so that DNA to cell mass is maintained at a constant ratio during cell division and DNA repair. Recombinant human RRM2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: R2, RR2, RR2M, Ribonucleoside-diphosphate reductase subunit M2 Ribonucleotide reductase M2 subunit, Ribonucleotide reductase small subunit,. NCBI no.: NP_001025
- Molecular Weight
- 47.0 kDa (409aa) confirmed by MALDI-TOF
- Pathways
- Mitotic G1-G1/S Phases
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