IL1RN Protein
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- Target See all IL1RN Proteins
- IL1RN (Interleukin 1 Receptor Antagonist (IL1RN))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- SDS-PAGE (SDS)
- Characteristics
- Interleukin-1 receptor antagonist, Human, Recombinant, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product IL1RN Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In Phosphate buffer saline (pH 7.4)
- Storage
- 4 °C
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- Target
- IL1RN (Interleukin 1 Receptor Antagonist (IL1RN))
- Alternative Name
- Interleukin-1 receptor antagonist (IL1RN Products)
- Synonyms
- DIRA Protein, ICIL-1RA Protein, IL-1RN Protein, IL-1ra Protein, IL-1ra3 Protein, IL1F3 Protein, IL1RA Protein, IRAP Protein, MVCD4 Protein, IRAP1 Protein, IL1RN Protein, IL-1RA Protein, F630041P17Rik Protein, interleukin 1 receptor antagonist Protein, interleukin 1 receptor antagonist-like Protein, IL1RN Protein, Il1rn Protein, IL1RNL Protein
- Background
- One of the most potent pro-inflammatory mediators is the early-acting cytokine interleukin-1 (IL-1), whose actions are regulated by the structurally related IL-1 receptor antagonist (IL-1 RA). IL-1 RA is a competitive IL-1 inhibitor and a powerful anti-inflammatory agent. Also, Several autoimmune and inflammatory diseases have been associated with an allelic polymorphism of the IL-1 RA gene. Recombinant human IL-1 RA was expressed in E. coli and purified by using conventional chromatography techniques. Synonyms: IL1RN, IL1F3, IL1RA, Interleukin-1 receptor antagonist , IL-1ra, IL-1RN, IRAP, IL1 inhibitor, ICIL-1RA, Anakinra, Interleukin-1 receptor antagonist protein, ICIL 1RA, IL1 inhibitor, ICIL1RA,. NCBI no.: NP_776214
- Molecular Weight
- 17.2kDa (153aa), confirmed by MALDI-TOF.
- Pathways
- NF-kappaB Signaling, Hormone Transport, Cancer Immune Checkpoints
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