IL1RN Protein

Catalog No. ABIN667037

Product Details

Target: IL1RN (Interleukin 1 Receptor Antagonist (IL1RN))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Characteristics: Interleukin-1 receptor antagonist, Human, Recombinant, E.coli

Purity: > 95 % by SDS - PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In Phosphate buffer saline (pH 7.4)

Storage: 4 °C

Target Details

Target: IL1RN (Interleukin 1 Receptor Antagonist (IL1RN))

Alternative Name: Interleukin-1 receptor antagonist (IL1RN Products)

Synonyms: DIRA Protein, ICIL-1RA Protein, IL-1RN Protein, IL-1ra Protein, IL-1ra3 Protein, IL1F3 Protein, IL1RA Protein, IRAP Protein, MVCD4 Protein, IRAP1 Protein, IL1RN Protein, IL-1RA Protein, F630041P17Rik Protein, interleukin 1 receptor antagonist Protein, interleukin 1 receptor antagonist-like Protein, IL1RN Protein, Il1rn Protein, IL1RNL Protein

Background: One of the most potent pro-inflammatory mediators is the early-acting cytokine interleukin-1 (IL-1), whose actions are regulated by the structurally related IL-1 receptor antagonist (IL-1 RA). IL-1 RA is a competitive IL-1 inhibitor and a powerful anti-inflammatory agent. Also, Several autoimmune and inflammatory diseases have been associated with an allelic polymorphism of the IL-1 RA gene. Recombinant human IL-1 RA was expressed in E. coli and purified by using conventional chromatography techniques. Synonyms: IL1RN, IL1F3, IL1RA, Interleukin-1 receptor antagonist , IL-1ra, IL-1RN, IRAP, IL1 inhibitor, ICIL-1RA, Anakinra, Interleukin-1 receptor antagonist protein, ICIL 1RA, IL1 inhibitor, ICIL1RA,. NCBI no.: NP_776214

Molecular Weight: 17.2kDa (153aa), confirmed by MALDI-TOF.

Pathways: NF-kappaB Signaling, Hormone Transport, Cancer Immune Checkpoints