desert Hedgehog Protein (AA 23-198) (His tag)
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- Target See all desert Hedgehog (DHH) Proteins
- desert Hedgehog (DHH) (Desert Hedgehog (DHH))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 23-198
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This desert Hedgehog protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- DHH, 23-198aa, Human, His-tagged, Recombinant, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product DHH Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid in 20mM MES pH 5.5, 0.5mM DTT, 20% glycerol
- Storage
- 4 °C
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- Target
- desert Hedgehog (DHH) (Desert Hedgehog (DHH))
- Alternative Name
- DHH (DHH Products)
- Synonyms
- GDXYM Protein, HHG-3 Protein, SRXY7 Protein, C78960 Protein, Xchh Protein, chh Protein, chh-a Protein, dhh Protein, dhh-1 Protein, dhh-A Protein, hh4 Protein, x-chh Protein, desert hedgehog Protein, desert hedgehog L homeolog Protein, desert hedgehog S homeolog Protein, DHH Protein, dhh Protein, Dhh Protein, dhh.L Protein, dhh.S Protein
- Target Type
- Species
- Background
- DHH belongs to the hedgehog family. The C-terminal domain displays an autoproteolysis activity and a cholesterol transferase activity. The N- terminal domain is the active species in both local and long-range signaling, whereas the C-terminal domain has no signaling activity. This protein is produced by Sertoli cells and may be involved in both male gonadal differentiation and perineurial development. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. Recombinant DHH protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Drosophila, HHG-3, MGC35145, Desert hedgehog protein N-product, DHH, desert hedgehog preproprotein Desert hedgehog, Desert hedgehog (Drosophila) homolog, Desert hedgehog homolog (Drosophila), Desert hedgehog protein precursor. NCBI no.: NP_066382
- Molecular Weight
- 22kDa (197aa), confirmed by MALDI-TOF.
- Pathways
- Hedgehog Signaling
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