DDC Protein (AA 1-480) (His tag)
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- Target See all DDC Proteins
- DDC (Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-480
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This DDC protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- Dopa decarboxylase, 1-480 aa Human, His-tagged, Recombinant, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product DDC Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 10% glycerol.
- Storage
- 4 °C
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- Target
- DDC (Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC))
- Alternative Name
- Dopa decarboxylase (DDC Products)
- Synonyms
- AADC Protein, wu:fa56d05 Protein, wu:fd59h03 Protein, wu:fk20h01 Protein, zgc:65801 Protein, zgc:76929 Protein, Ddc Protein, DdcDv Protein, Dvir\\GJ17995 Protein, GJ17995 Protein, dvir_GLEANR_2561 Protein, Aadc Protein, 5-HT Protein, CG10697 Protein, DDC Protein, DdcDm Protein, Dmel\\CG10697 Protein, ddc Protein, fDDC Protein, l(2)37Bl Protein, l(2)37Ch Protein, l(2)k02104 Protein, dopa decarboxylase Protein, Dopa-decarboxylase Protein, dopa decarboxylase (aromatic L-amino acid decarboxylase) Protein, Dopa decarboxylase Protein, dopa decarboxylase L homeolog Protein, DDC Protein, ddc Protein, Ddc Protein, Dvir\Ddc Protein, ddc.L Protein
- Background
- Dopa decarboxylase, also known as DDC, is a homodimeric, pyridoxal phosphate dependent enzyme. Dopa decarboxylase is a protein implicated in 2 metabolic pathways, synthesizing 2 important neurotransmitters: dopamine and serotonin which both play key roles in many clinical disorders, including Parkinson’s disease. Dopa decarboxylase is found in different areas of the brain and is particularly abundant in basal ganglia. Recombinant human Dopa decarboxylase protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: DDC, AADC, Aromatic L-amino acid decarboxylase, L-Dopa decarboxylase, Aromatic L Amino Acid Decarboxylase. NCBI no.: NP_001076440
- Molecular Weight
- 56.4 kDa (503aa), confirmed by MALDI-TOF.
- Pathways
- Dopaminergic Neurogenesis
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