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UGDH Protein (AA 1-494) (His tag)

UGDH Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS-PAGE SDS
Catalog No. ABIN667140
  • Target See all UGDH Proteins
    UGDH (UDP-Glucose 6-Dehydrogenase (UGDH))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-494
    Origin
    • 6
    • 3
    • 1
    • 1
    • 1
    Human
    Source
    • 4
    • 3
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This UGDH protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    UGDH, 1-494aa, Human, His tag, E.coli
    Purity
    > 95 % by SDS-PAGE
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 20% glycerol, 1mM DTT, 0.1M NaCl, and 1mM EDTA.
    Storage
    4 °C
  • Target
    UGDH (UDP-Glucose 6-Dehydrogenase (UGDH))
    Alternative Name
    UGDH (UGDH Products)
    Synonyms
    8310 Protein, BG01214 Protein, CG10072 Protein, Dmel\\CG10072 Protein, Sgl Protein, UDP-GlcDH Protein, UDPGDH Protein, XIII Protein, kiwi Protein, l(3)05007 Protein, l(3)08310 Protein, l(3)10503 Protein, l(3)65CEd Protein, l(3)SG9 Protein, ska Protein, sl Protein, ik:tdsubc_2a8 Protein, tdsubc_2a8 Protein, xx:tdsubc_2a8 Protein, gdh Protein, ugd Protein, ugdh Protein, ugdhb Protein, xugdh Protein, udpgdh Protein, udpg Protein, ugdha Protein, BA5434 Protein, SCBAC19G2.07 Protein, AGR_L_1413 Protein, udg Protein, GDH Protein, UGD Protein, Udpgdh Protein, sugarless Protein, UDP-glucose 6-dehydrogenase Protein, UDP-glucose 6-dehydrogenase L homeolog Protein, UDP-glucose 6-dehydrogenase S homeolog Protein, UDP-glucose dehydrogenase WcvB Protein, UDP-glucose dehydrogenase Protein, sgl Protein, ugdh Protein, ugdh.L Protein, UGDH Protein, ugdh.S Protein, hasB Protein, ugdH Protein, ugd Protein, SCO3052 Protein, wcvB Protein, CNL06460 Protein, Ugdh Protein
    Background
    UGDH is a member of the UDP-glucose/GDP-mannose dehydrogenase family and is a ubiquitously expressed protein most abundant in the liver. This protein converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. Recombinant human UGDH protein, fused to his-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: GDH, UDP-GlcDH, UDPGDH, UGD, UDP-glucose dehydrogenase, UDP-glucose 6-dehydrogenase. NCBI no.: NP_003350
    Molecular Weight
    59.5 kDa (533aa) confirmed by MALDI-TOF
    Pathways
    Glycosaminoglycan Metabolic Process
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