HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2) (AA 1-242) protein (His tag)
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- Target See all HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2) Proteins
- HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-242
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- His tag
- Application
- SDS-PAGE (SDS)
- Characteristics
- HTATIP2, 1-242aa, Human, His tag, E.coli
- Purity
- > 95 % by SDS- PAGE
- Top Product
- Discover our top product HTATIP2 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 1mM DTT
- Storage
- 4 °C
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- Target
- HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2)
- Alternative Name
- HTATIP2 (HTATIP2 Products)
- Synonyms
- htatip2 Protein, MGC89074 Protein, HTATIP2 Protein, fb15b04 Protein, tip30 Protein, wu:fb15b04 Protein, CC3 Protein, SDR44U1 Protein, TIP30 Protein, AW111545 Protein, Cc3 Protein, Tip30 Protein, HIV-1 Tat interactive protein 2 Protein, HIV-1 Tat interactive protein 2 L homeolog Protein, HTATIP2 Protein, htatip2 Protein, Htatip2 Protein, htatip2.L Protein
- Target Type
- Viral Protein
- Background
- HTATIP2, also known as TIP30, is a member of the short-chain dehydrogenases/reductases (SDR) family. It acts as a tumor suppressor participating in metabolic suppression, inhibition of angiogenesis and induces the expression of apoptosis related genes Bad and Siva. HTATIP2 interacts with the activation domain of HIV-1 TAT and enhances its transcription by phosphorylating RNA polymerase II (Pol II). Defects in This protein are associated with hepatocellular carcinomas and apoptotic resistant tumor cells, suggesting a potential use for HTATIP2 in antitumor therapy. Recombinant human HTATIP2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: CC3, TIP30, SDR44U1, Oxidoreductase HTATP2, HTATIP 2, HTATIP-2, CC-3, TIP 30, TIP-30. NCBI no.: AAH15358
- Molecular Weight
- 29.3 kDa (262aa), confirmed by MALDI-TOF
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