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BIN1 Protein (AA 1-439) (His tag)

BIN1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS – PAGE SDS
Catalog No. ABIN667182
  • Target See all BIN1 Proteins
    BIN1 (Bridging Integrator 1 (BIN1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-439
    Origin
    • 7
    • 1
    • 1
    Human
    Source
    • 3
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This BIN1 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    BIN1, 1-439aa, Human, His tag, E.coli
    Purity
    > 90 % by SDS – PAGE
    Top Product
    Discover our top product BIN1 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris buffer(pH 8.0) containing 10% glycerol, 1mM DTT
    Storage
    4 °C
  • Target
    BIN1 (Bridging Integrator 1 (BIN1))
    Alternative Name
    BIN1 (BIN1 Products)
    Synonyms
    bin1 Protein, MGC53185 Protein, amph2 Protein, amphl Protein, sh3p9 Protein, MGC76187 Protein, cb57 Protein, zgc:86701 Protein, BIN1 Protein, AMPH2 Protein, AMPHL Protein, SH3P9 Protein, ALP-1 Protein, Amphl Protein, BRAMP-2 Protein, bridging integrator 1 Protein, bridging integrator 1 S homeolog Protein, bridging integrator 1b Protein, BIN1 Protein, bin1.S Protein, bin1 Protein, bin1b Protein, Bin1 Protein
    Background
    BIN1, also known as SH3P9, is a nucleocytoplasmic adaptor protein, one of which was initially identified as MYC-interacting protein with features of a tumor suppressor. This protein interacts with and inhibits the oncogenic activity of the myc oncoprotein that has a major role in many human cancers. The loss of Bin1 may contribute to growth deregulation in cancer cells in carcinoma of the breast, colon, lung, cervix, prostate and liver. Recombinant human BIN1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: AMPH2, AMPHL, MGC10367, SH3P9, Amphiphysin II, Myc box-dependent-interacting protein 1. NCBI no.: AAH04101
    Molecular Weight
    50.4 kDa (459aa) confirmed by MALDI-TOF
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