PGAM1 Protein (AA 1-254) (His tag)
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- Target See all PGAM1 Proteins
- PGAM1 (phosphoglycerate Mutase 1 (Brain) (PGAM1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-254
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PGAM1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- PGAM1, 1-254aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS – PAGE
- Top Product
- Discover our top product PGAM1 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 1mM DTT
- Storage
- 4 °C
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- Target
- PGAM1 (phosphoglycerate Mutase 1 (Brain) (PGAM1))
- Alternative Name
- PGAM1 (PGAM1 Products)
- Synonyms
- PGAM-B Protein, PGAMA Protein, Pgmut Protein, MGC81450 Protein, 2310050F24Rik Protein, Pgam-1 Protein, pgam1 Protein, wu:fb81h05 Protein, fd15c02 Protein, pgam1lb Protein, wu:fd15c02 Protein, zgc:63722 Protein, phosphoglycerate mutase 1 Protein, phosphoglycerate mutase 1 L homeolog Protein, phosphoglycerate mutase 1a Protein, phosphoglycerate mutase 1b Protein, PGAM1 Protein, Pgam1 Protein, pgam1.L Protein, pgam1 Protein, pgam1a Protein, pgam1b Protein
- Background
- PGAM1 belongs to the phosphoglycerate mutase family. This protein is important components of glucose and 2,3-BPGA (2,3-bisphosphoglycerate) metabolism and catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. The PGAM is a dimeric enzyme containing, in different tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB). Mutations in this protein cause muscle phosphoglycerate mutase eficiency, also known as glycogen storage disease X. Recombinant human PGAM protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Phosphoglycerate mutase isozyme B, PGAM-B, PGAMA, Phosphoglycerate mutase 1. NCBI no.: NP_002620
- Molecular Weight
- 30.9 kDa (274aa), confirmed by MALDI-TOF
- Pathways
- Regulation of Carbohydrate Metabolic Process
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