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PGAM1 Protein (AA 1-254) (His tag)

PGAM1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS – PAGE SDS
Catalog No. ABIN667196
  • Target See all PGAM1 Proteins
    PGAM1 (phosphoglycerate Mutase 1 (Brain) (PGAM1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-254
    Origin
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 6
    • 3
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This PGAM1 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    PGAM1, 1-254aa, Human, His tag, E.coli
    Purity
    > 90 % by SDS – PAGE
    Top Product
    Discover our top product PGAM1 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 1mM DTT
    Storage
    4 °C
  • Target
    PGAM1 (phosphoglycerate Mutase 1 (Brain) (PGAM1))
    Alternative Name
    PGAM1 (PGAM1 Products)
    Synonyms
    PGAM-B Protein, PGAMA Protein, Pgmut Protein, MGC81450 Protein, 2310050F24Rik Protein, Pgam-1 Protein, pgam1 Protein, wu:fb81h05 Protein, fd15c02 Protein, pgam1lb Protein, wu:fd15c02 Protein, zgc:63722 Protein, phosphoglycerate mutase 1 Protein, phosphoglycerate mutase 1 L homeolog Protein, phosphoglycerate mutase 1a Protein, phosphoglycerate mutase 1b Protein, PGAM1 Protein, Pgam1 Protein, pgam1.L Protein, pgam1 Protein, pgam1a Protein, pgam1b Protein
    Background
    PGAM1 belongs to the phosphoglycerate mutase family. This protein is important components of glucose and 2,3-BPGA (2,3-bisphosphoglycerate) metabolism and catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. The PGAM is a dimeric enzyme containing, in different tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB). Mutations in this protein cause muscle phosphoglycerate mutase eficiency, also known as glycogen storage disease X. Recombinant human PGAM protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Phosphoglycerate mutase isozyme B, PGAM-B, PGAMA, Phosphoglycerate mutase 1. NCBI no.: NP_002620
    Molecular Weight
    30.9 kDa (274aa), confirmed by MALDI-TOF
    Pathways
    Regulation of Carbohydrate Metabolic Process
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