PFDN1 Protein (AA 14-122) (His tag)
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- Target See all PFDN1 Proteins
- PFDN1 (Prefoldin Subunit 1 (PFDN1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 14-122
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PFDN1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- PFDN1, 14-122aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product PFDN1 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 20% Glycerol
- Storage
- 4 °C
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- Target
- PFDN1 (Prefoldin Subunit 1 (PFDN1))
- Alternative Name
- PFDN1 (PFDN1 Products)
- Synonyms
- PFDN1 Protein, 2700086I23Rik Protein, AA408327 Protein, AU044714 Protein, PDF Protein, PFD1 Protein, zgc:110742 Protein, prefoldin subunit 1 Protein, prefoldin 1 Protein, prefoldin subunit 1 S homeolog Protein, PFDN1 Protein, AFUA_4G12360 Protein, pfdn1 Protein, Pfdn1 Protein, pfdn1.S Protein
- Background
- PFDN1 is one of sixsubunits of prefoldin, a heterohexameric chaperone protein which assists in the correct folding of other proteins. This protein delivers nonnative target proteins, principally actins and tubulins, to the eukaryotic cytosolic chaperonin for facilitated folding. Defects in PFDN1 displayed phenotypes characteristic of defects in cytoskeletal function, including manifestations of ciliary dyskinesia, neuronal loss, and defects in B and T cell development and function. Recombinant human PFDN1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Prefoldin subunit 1, PDF, PFD1. NCBI no.: NP_002613
- Molecular Weight
- 15.0kDa (130aa), confirmed by MALDI-TOF
- Pathways
- Unfolded Protein Response
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