RDBP Protein (AA 1-380) (His tag)
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- Target See all RDBP Proteins
- RDBP (RD RNA Binding Protein (RDBP))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-380
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This RDBP protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- RDBP, 1-380aa, Human, His tag, E.coli
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product RDBP Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 2mM DTT, 0.1M NaCl.
- Storage
- 4 °C
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- Target
- RDBP (RD RNA Binding Protein (RDBP))
- Alternative Name
- RDBP (RDBP Products)
- Synonyms
- CG5994 Protein, Dmel\\CG5994 Protein, NELF Protein, NELF-E Protein, Nelf-e Protein, anon-66Da Protein, cg5994 Protein, dNelf-E Protein, D6S45 Protein, RD Protein, RDBP Protein, RDP Protein, Rd Protein, Rdbp Protein, D17H6S45 Protein, Negative elongation factor E Protein, negative elongation factor complex member E Protein, negative elongation factor complex member E, Rdbp Protein, Nelf-E Protein, NELFE Protein, Nelfe Protein
- Background
- RDBP, also known as NELF-E, is a putative RNA binding protein. This protein is one of the five components of the multisubunit NELF complex that cooperates with DSIF to repress RNA polymerase II elongation. Control of transcription elongation requires a complex interplay between positive transcription elongation factor b and negative transcription elongation factors, DSIF and NELF. DSIF and NELF, act as negative transcription elongation factors by increasing the time the polymerase spends at pause sites. RDBP has a functional RNA-binding domain, whose mutations impair transcription repression without affecting known protein-protein interactions. Recombinant human RDBP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: RD RNA binding protein, D6S45, NELF-E, RD, RDP. NCBI no.: NP_002895
- Molecular Weight
- 45.4 kDa (400aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
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